The news means the likes of Jacob Butterfield, Alex Marrow, Stuart O'Keefe and Jonathan Williams are Holloway's only senior options for a starting place in the middle of the park.
Influential skipper Jedinak was on the end of nasty challenge from Huddersfield Town forward Alan Lee on Wednesday night, and Holloway is still reeling from the outcome 48 hours on.
"Mile will be out for another four days until he can play with a mask on," Holloway told Advertiser Sport after his Friday press conference at the club's training ground.
"It will be Phantom of the Opera style, but his eye is totally still closed."
And Moritz, who suffered an ankle injury on the stroke of half-time in West Yorkshire, is set for a longer spell on the sidelines.
"Andre is out for six weeks," said the boss.
"He twisted his ankle and he heard a 'pop', so there might be a ligament gone there or somewhere along the line.
"It's still too swollen to get it scanned."
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